A Single Severe Head Injury Can Trigger Long-Term Brain Damage

Source: newscientist.com | Repost Duerson Fund 3/20/2020 –

One major blow to the head is enough to trigger progressive brain deterioration and long-term cognitive decline in some people.

We already know that repeated head knocks – like those sustained in boxing and American football – can lead to personality changes, cognitive problems and depression years later. This condition – known as chronic traumatic encephalopathy (CTE) – is associated with gradual build-up of a protein called tau in the brain.

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David Sharp at Imperial College London and his colleagues wondered if similar brain changes can occur after one bad head injury.

To find out, they scanned the brains of 21 men and women who had a single major head injury 18 to 51 years ago in a car accident, assault or fall. They all experienced severe initial symptoms like loss of consciousness for more than 30 minutes, and many have since developed problems with thinking, memory and motivation.

The scans revealed that 15 of the participants have unusually high levels of tau protein in their brains, particularly in the outer layers. This is probably because the outer layers are most vulnerable to external impacts, Sharp’s team writes.

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